management of dyslipidemia ppt

management of dyslipidemia ppt2022/04/25

Hypertension and Dyslipidemia constitute the important components of metabolic syndrome as per the definition of NCEP Guidelines-Adult Treatment Panel III (ATP III). Dyslipidemia Management ## nonpharmacological therapy; *reduce intake of saturated and trans-unsaturated fat *reduce cholesterol intake *reduce dense energy food *reduce alcohol *increase vegetables, unrefined carbohydrates, fibers, fruits *increase fish, omega 3 FA *wt loss, exercise, smoking and dealing with other modifiable CV risk factors To that end, this CPG is intended to guide providers who care for patients with dyslipidemia along management pathways supported by evidence. A sedentary lifestyle with excessive dietary intake of total calories, saturated fat, cholesterol, and . to promote appropriate treatment of dyslipidemia, the korean society of lipid and atherosclerosis (kso-la) published the first guidelines for the management of hyperlipidemia in 1996, the second guideline in 2003, the second revision in 2009, and the third guidelines for treatment of dyslipidemia with added contents in 2015, in collaboration with … . They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. It leads to a number of health-related complications and reduces life expectancy. The Dyslipidemia Clinical Topic Collection gathers the latest guidelines, news, JACC articles, education, meetings and clinical images pertaining to its cardiovascular topical area — all in one place for your convenience. therapy) to help patients in acute stroke settings. PowerPoint is the world's most popular presentation software which can let you create professional Dyslipidemia and Atherosclerosis powerpoint presentation easily and in no time. Management of dyslipidemia Amir M. Hanafi PGY1 2. Download Download PDF. Director, Metabolism Section Cardiovascular Genetics | PowerPoint PPT presentation | free to view this algorithm for the comprehensive management of dyslipidemia and prevention of cardiovascular disease (cvd) complements the 2017 american association of clinical endocrinologists/american college of endocrinology (aace/ace) guidelines for management of dyslipidemia and prevention of cardiovascular disease and provides clinicians with a … MANAGEMENT-The management of lipid disorder greatly depends on the age, signs/symptoms of the affected persons. Do you have PowerPoint slides to share? 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk . DYSLIPIDEMIA - A consequence of abnormal lipoprotein metabolism - It includes: - High total cholesterol - High low-density lipoproteins (LDL) - High triglycerides (TG) - Low high-density lipoproteins (HDL) 3. Keywords: drug interactions, fibrates, fish oil, guidelines, HIV-associated dyslipidemia, hypertriglyceridemia, niacin, statins • Three primary abnormality are there Elevated triglyceride (TG) Elevated LDL cholestrol Reduced HDL cholestrol • It is most important modifiable risk factor for CAD. A 50-year-old white woman with a recent history of multiple myocardial infarctions presented for management of dyslipidemia. PowerPoint Presentation Last modified by: Carranza leon, Barbara Gisella . Guidelines are no substitutes but are complements for textbooks and cover the ESC Core Curriculum topics. The management of dyslipidemia, a well-recognized and modifiable risk factor among patients with type 2 diabetes, is an important element in the multifactorial approach to prevent coronary heart disease. The system-wide goal of evidence-based guidelines is to improve the patient's health and well-being. LipidsLipids are a family of non-polar organic noncompounds that are characterized by their insolubility in water but dissolve in organic solvents. Improvements in the SOT continuum of care have unmasked a significant burden of cardiovascular disease, manifesting as a leading cause of morbidity and mortality. Primary dyslipidemia 2. World's Best PowerPoint Templates - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. Co-Chair Patients with high or very high-risk ASCVD are those with multiple major ASCVD events or one major ASCVD event and multiple high-risk conditions. The prevalence of the co-existence of hypertension and dyslipidemia is in . Halawani et al.Diagnosis and Management of Dyslipidemia 68 Archives of Pharmacy Practice ¦ Volume 10 ¦ Issue 4 ¦ October-December 20191 Dyslipidemia is one of the most common risk factors noted in patients with cardiovascular disease (such as atherosclerosis). Dyslipidemia is a prerequisite to the development of atherosclerotic cardiovascular disease. The recommendations should serve as guidance to clinicians for treating patients with dyslipidemia. Associate Professor of Medicine. erol >200 mg%, Low density lipoprotein (LDL) >100 mg%, Triglycerides (TGL) >150 mg% and High density lipoprotein (HDL) <40 mg in men and < 50 mg in women. Study cohort: 37,304 assessed for dyslipidemia. Dairy products and red meat are taken in moderation. He continues to pursue his passion in the field of acute stroke management and plans to set up a Stroke Institute. Initial management for dyslipidemia involves lifestyle modifications. Draft Part Two The NLA Recommendations for Patient-Centered Management of Dyslipidemia, published in the Journal of Clinical Lipidology, re-affirm the importance of cholesterol goals for the prevention of heart attack and stroke. Diabetic dyslipidemia is a cluster of lipoprotein abnormalities characterized by increased triglyceride level, decreased high-density lipoprotein-cholesterol levels and increase in small dense low-density lipoprotein (LDL) particles. Objectives 1. Review current guidelines regarding use of statin medications in the treatment and prevention of ASCVD. Case summary At baseline, the patient had elevated low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC), and Lp(a) (306 nmol/L) levels and low high-density lipoprotein cholesterol (HDL-C . Chair: Paul S. Jellinger, MD, MACE. Causes of Dyslipidemia. 11/15/2016. The Menace of Obesity, its Health Hazards and Management - Simply put, obesity is a state of excess accumulation of fat in the body. 1. 3. For those with T2DM at high risk, an LDL-C reduction of at least 50% from baseline and an LDL-C goal of . Predictive value = 20.7%. J Res Med Sci 2015;20:1191-9. Major ASCVD events . Alcohol overindulgence. Based on AHA guidelines of 2013 4. American Association of Clinical Endocrinologists and American College of Endocrinology Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease. trans fats. how to manage low hdl levels. Blood lipids are fatty substances, such as triglycerides and cholesterol. The following are remedies / treatment may apply to lower the level of LIPIDS in the body including:Eat well-balanced diet Almost fifteen (15) percent of cholesterol may decrease when strictly controlled. As with blood pressure, lipid levels track through childhood. Dyslipidemia is the imbalance of lipids such as cholesterol, low-density lipoprotein cholesterol, (LDL-C), triglycerides, and high-density lipoprotein (HDL). • When the LDL-C cut-off value was strictly set to 100 mg/dL, more than 85% of people with diabetes had dyslipidemia. The PowerPoint PPT presentation: "Dyslipidemia/Lipid management in Diabetes" is the property of its rightful owner. . Management of Dyslipidemia: Expert Opinion on Diagnosis and Treatment Lecture Share . Drugs. Yusuf S, Islam S, Chow CK, et al. Classification. Piedmont Heart Institute. The health hazards of obesity include hypertension, type 2 diabetes, dyslipidemia, cancer, liver disease, reproductive disorders, heart disease, mood disorders, etc. Primary dyslipidemia is inherited. Topic (s): Coronary Artery Disease (Chronic) Cardiovascular Disease in Primary Care Based on AHA guidelines of 2013 4. Causes of Dyslipidemia. These novel ESC/EAS Guidelines on lipids provide important new advice on patient management, which should enable more clinicians to efficiently and safely reduce CV risk through lipid modification. The dyslipidemia of type 2 diabetes is characterized by high triglyceride levels and decreased high-density lipoprotein (HDL) cholesterol, changes observed many years before the onset of clinically relevant hyperglycemia [9, 30].Recent evidence suggests that low HDL cholesterol is an independent factor not only for cardiovascular disease but also for the development of diabetes itself []. Secondary dyslipidemia 4. Effective management of dyslipidemia in this population is essential to reduce cardiovascular risk but presents multiple challenges due to interactions between antiretroviral therapy agents and lipid-lowering medications. Lifestyle . In the clinical management of dyslipidemia, a reasonable goal is to strive for lipid levels in the normal range; however, more aggressive goals need to be set for higher-risk individuals. ESC National Cardiac Societies. . Only in populations with lifelong hypocholesterolemia is a near absence of clinical coronary heart disease (CHD) observed. Abstract and Introduction. ment of dyslipidemia by teaching their primary care col- 10. Consequently, a recommendation to update the 2014 VA/DoD Dyslipidemia CPG was initiated in 2019. PPT - Management of Dyslipidemia PowerPoint presentation Simplified lipid guidelines Prevention and management of cardiovascular disease in primary care ment of dyslipidemia, and whether the use of cholesterol Guidelines. CHOLESTEROL. Disorders) Secondary Causes . Persons with diabetes have an increased CV risk, which is even further increased by atherogenic dyslipidemia. Objectives • To know who are the Major 4 statin benefit groups • To know how to calculate ASCVD risk • To have a clear understanding of how statins are used in the 4 benefit groups • To know the need to address hypertriglyceridemia. Educational information. This report provides comprehensive information on the therapeutic development for Dyslipidemia, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. Objectives To know who are the Major 4 statin benefit groups To know how to calculate ASCVD risk To have a clear understanding of how statins are used in the 4 benefit groups To know the need to address hypertriglyceridemia. The impact of recent trial data on management strategies in older patients is . A sedentary lifestyle with excessive dietary intake of total calories, saturated fat, cholesterol, and . Management of diabetic dyslipidemia: An update World J Diabetes. Indian the lead in the domains of CAD, its risk factors and manage- Heart J. Clinical Practice Guidelines on the Management of Dyslipidemia in the Philippines (2005 CPG). B. Gisella Carranza Leon, MD. 2011;128 Kelishadi R, Haghdoost AA, Moosazadeh M, Keikha M, Aliramezany M. A systematic review and meta-analysis on screening lipid disorders in the pediatric age group. It is extremely common in type 2 diabetes (T2DM) affecting around 70 % of patients. DYSLIPIDEMIA. Results: Sensitivity = 42.65% / Specificity = 59%. 2014;66:S1eS51. Predictive value = 20.7%. Lack of awareness of current guidelines ; The PowerPoint PPT presentation: "Dyslipidemia" is the property of its rightful owner. Dyslipidemia may be tolerated, even if it cannot be treated optimally. Evolocumab (Repatha) for the Treatment of Hyperlipidemia [STEPS] 08/15/2016. triglycerides, phospholipids, Lipids includes triglycerides phospholipids sterols and fat soluble vitamins. Introduction • Dyslipidemia is a disorder of Lipid & lipoprotein metabolism. Kwiterovich P. Recognition and Management of Dyslipidemia in Children and Adolescents. An atherogenic profile in patients with type 2 diabetes is termed diabetic dyslipidemia. The health hazards of obesity include hypertension, type 2 diabetes, dyslipidemia, cancer, liver disease, reproductive disorders, heart disease, mood disorders, etc. Dyslipidemia is defined as having blood lipid levels that are too high or low. A panel of experts in the fields of dyslipidemia, cardiology, endocrinology and epidemiology were assembled to comprise the technical research committee (TRC) tasked to review available clinical evidence on dyslipidemia management. Solid organ transplantation (SOT) has revolutionized treatment of end-stage disease. Broadly, risk factors are arbitrarily divided into three major categories: nonmodifiable, modifiable, and emerging. Winner of the Standing Ovation Award for "Best PowerPoint Templates" from Presentations Magazine. Pediatrics. title = "Contemporary Management of Dyslipidemia", abstract = "The treatment of dyslipidemia continues to be a dynamic and controversial topic. Primary Causes. About 10%-25% of myocardial infarctions (MI) in India occur before the age of 40 years4,5 and more than 50% of CAD-associated deaths in India occur before the age of 50 years.3-5. It leads to a number of health-related complications and reduces life expectancy. Global Dyslipidemia Drugs Market Insight and Forecast to 2026 - The research team projects that the Dyslipidemia Drugs market size will grow from XXX in 2019 to XXX by 2026, at an estimated CAGR of XX. Furthermore, with ever-increasing . Writing Committee . In the elderly age group, as in the younger age group, lowering of the concentration of cholesterol containing atherogenic particles via lipid lowering therapies, is effective in reducing cardiovascular risk. Writing Committee . Multiple gene mutations that result in either . Clin. low hdl levels can be treated with- 1) statins produce modest elevations in hdl-c 2)nicotinic acid-nicotinic acid appears to increase hdl-c by partially reducing hdl catabolism and mainly by increasing apo a1 synthesis by the liver. • Causes for dyslipidemia 1. Lifestyle . Diabetes . This helps you give your presentation on Dyslipidemia and Atherosclerosis in a conference, a school lecture, a business proposal, in a webinar and business and professional representations. Statins and other lipid lowering therapies reduce CV risk in these patients. Disease and Background About 69% of U.S. adults have LDL-C >100mg/dl The prevalence is double in obese individual with elevated triglyceride level > 33% About 70-80% of patients with dyslipidemia does not meet the LDL-C targets despite lipid therapy, management, and treatment (Jellinger, et al., 2017). Although multiple risk factors including smoking, sedentary lifestyle, obesity, hypertension and diabetes are all important contributors to ASCVD, dyslipidemia is the . Hyperlipidemia: Drugs for Cardiovascular Risk Reduction in Adults. trans fats. This condition can result from diet, tobacco exposure, or genetic and can lead to cardiovascular disease with severe complications. Management of Post-transplant hyperlipidemia. 2008 S1-44. Guidelines for dyslipidemia Ref.> Dyslipidemia fact sheets in Korea. KaveyREW et al. Lifestyle and medical therapies can be used to treat this condition, leading to major changes in circulating lipids. 1. The base year considered for the study is 2019, and the market size is projected from 2020 to 2026. This activity describes the evaluation and management of . For patients with type 2 diabetes mellitus (T2DM) at very-high risk, an LDL-C reduction of at least 50% from baseline and an LDL-C goal of below 1.4 mmol/L (<55mg/dL) is recommended. Guidelines in the treatment of dyslipidemia in primary and secondary prevention for acute coronary syndrome. Drugs. This approach should include a diet with an emphasis on the intake of vegetables, fruits, and whole grains within an appropriate calorie requirement. Dyslipidemia is divided up into primary and secondary types. or assisting physicians in selecting the best management strategies for an individual patient, with a given condition, taking into account the impact on outcome, as well as the risk-benefit ratio of particular diagnostic or therapeutic means. Although several risk factors for development of post-transplant cardiovascular disease exist, dyslipidemia remains one of the most frequent and . Metab. J Res Med Sci 2015;20:1191-9. Chair: Paul S. Jellinger, MD, MACE. × Authors Ishwarlal Jialal 1 , Gurdeep Singh 2 Affiliations 1 California North-state University College of . (fibrates has a small ability to … Alirocumab (Praluent) for Treatment of . The Image and Slide Gallery captures images, videos, or slides which can serve as useful teaching materials in the field of CV medicine. The effect of PCSK9 inhibitors on non-HDL-c levels and clinical events was demonstrated in patients with diabetes. This chapter provides an overview of the important factors to be considered during the decision-making process of recommending a lipid lowering medication to an older patient. Dyslipidemia.Definition. Management of dyslipidemia for the secondary prevention of ASCVD is centered on encouragement of intensive healthy lifestyle modifications and risk assessment for future ASCVD. 2019 ESC/EAS Guidelines on management of dyslipidaemias Lipid modification to reduce cardiovascular risk. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk (European Heart Journal 2019 -doi: 10.1093/eurheartj/ehz455) treatment. overproduction . The increased cardiovascular disease (CVD) risk associated with type 2 diabetes (T2D) is likely due in part to diabetic dyslipidemia—a condition characterized by elevated plasma levels of triglyceride‐rich lipoproteins (TRLs), smaller denser LDL particles, and decreased HDL cholesterol (1,2).Lifestyle modifications and statins are first-line interventions for CVD risk reduction in . 3. Denise Reedus , N.P. The rationale for the treatment of diabetic dyslipidemia is discussed in detail in the American Diabetes Association (ADA) technical review "Management of Dyslipidemia in Adults With Diabetes" ().Type 2 diabetes is associated with a two- to fourfold excess risk of cardiovascular disease (CVD). Study cohort: 37,304 assessed for dyslipidemia. Diagnosis. overproduction . The guidelines that cover the screening of patients for elevated serum lipid levels, and the treatment of patients with lipid abnormalities, rest on calculations of individual patients' risk for a future cardiovascular event. Use of secondary prevention leagues, medical students and physicians . These guidelines has been developed for healthcare professionals to facilitate informed communication with individuals about their CV risk and the benefits of adopting and sustaining a healthy lifestyle, and of early modification of their lipid-related CV risk. In this chapter, we review the causes, therapies, and changes in outcomes due to treatment of hyperlipidemias in patients with diabetes. The Menace of Obesity, its Health Hazards and Management - Simply put, obesity is a state of excess accumulation of fat in the body. Diabetic dyslipidemia typically consists of elevated triglyceride, low high-density lipoprotein cholesterol (HDL-C), and the predominance of . J . Hypothyroidism. Autopsy studies have consistently demonstrated the adolescent onset . This algorithm for the comprehensive management of dyslipidemia and prevention of cardiovascular disease (CVD) complements the 2017 American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease and provides clinicians with a practical guide that considers the whole patient, their . Endocrinol. 2. Results: Sensitivity = 42.65% / Specificity = 59%. As shown in Table 1, AACE has defined 5 risk categories based on the number and severity of major risk factors (see Table 2). or Foods that are sugary and fried must be avoided. Alcohol overindulgence. Dyslipidemia is elevation of plasma cholesterol, triglycerides (TGs), or both, or a low high-density lipoprotein cholesterol level that contributes to the development of atherosclerosis Atherosclerosis Atherosclerosis is characterized by patchy intimal plaques (atheromas) that encroach on the lumen of medium-sized and large arteries; the plaques contain lipids, inflammatory cells, smooth muscle. The Image and Slide Gallery captures images, videos, or slides which can serve as useful teaching materials in the field of CV medicine. Secondary dyslipidemia is an acquired condition. Also, adults should participate in moderate to vigorous aerobic physical activity 3 to 4 times a week for at least 40 minutes. A soft waxy substance found among lipids (fats) in the bloodstream and all cells Needed for digesting fats, making hormones, building cell walls. American Association of Clinical Endocrinologists and American College of Endocrinology Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease. • Adopt healthy lifestyle • Consume healthy diet • Incorporate exercise • Quit smoking • Conduct 10-year ASCVD risk estimation for adults 40-75 • Promote healthy lifestyle and evaluate for pharmacotherapy for adults with DM • Use statin therapy first-line in at-risk patients • Aspirin not routinely recommended Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents: Summary Report. • The prevalence of dyslipidemia in adults with diabetes is 2 times higher than that of the adults without diabetes. During the past 3 years, the treatment of dyslipidemia has evolved significantly. Multiple gene mutations that result in either . The main objective for 2019 May 15;10(5):280-290. doi: 10.4239/wjd.v10.i5.280. Cardiologists, rightly so, should take on management of dyslipidemia in Indian subjects. A New Age of Dyslipidemia Treatment: Role of Non-Statin Therapies BRODY MAACK, PHARMD, BCACP, CTTS . Dyslipidemia therapy in the setting of diabetes mellitus. Diabetes . CHOLESTEROL • A soft waxy substance found among . Full PDF Package Download Full PDF Package. Dyslipidemia Treatment A. Non-Pharmacologic Treatment Therapeutic Lifestyle Change- diet plans include foods that are low in cholesterol and calories and trans-fat free. Even the most appropriate therapeutic range for lipid levels—including that of triglycerides and low-density lipoprotein cholesterol—remain actively debated. L-TAP 2, a multinational survey of 9955 adults with dyslipidemia (75% receiving statin therapy), found LDL-C goal attainment rates of 86%, 74%, and 67% for individuals at low (≤1 risk factor . Management. PPT - DYSLIPIDEMIA PowerPoint Presentation, free download - ID:534652. Can I get a copy of the PowerPoint slides used in the live lectures? Hypothyroidism. Kelishadi R, Haghdoost AA, Moosazadeh M, Keikha M, Aliramezany M. A systematic review and meta-analysis on screening lipid disorders in the pediatric age group. . To promote appropriate treatment of dyslipidemia, the Korean Society of Lipid and Atherosclerosis (KSo-LA) published the first guidelines for the management of hyperlipidemia in 1996, the second guideline in 2003, the second revision in 2009, and the third guidelines for treatment of dyslipidemia with added contents in 2015, low hdl levels increase the risk of ihd. Genetic Causes(Familial. Edin Begic. Discuss the clinical use and available evidence of PCSK-9 inhibitors Primary Causes. Management of Diabetic Dyslipidemia: Recent Advances in Combination Therapy - Management of Diabetic Dyslipidemia: Recent Advances in Combination Therapy Eliot A. Brinton, M.D. Disorders) Secondary Causes . Genetic Causes(Familial. If so, share your PPT presentation slides online with PowerShow.com. Each category has goals for LDL . Co-Chair Clinical Advances in Treating Across the Cardiovascular Continuum: Atherosclerotic Cardiovascular Disease and Heart Failure Major strides in dyslipidemia management have been made in the last few years, from science-based advances to recognition of critical risk factors, such as low density lipoprotein cholesterol (LDL-C) and lipoprotein a (Lp[a]) among others, as well as the arrival of . Management of dyslipidemia Amir M. Hanafi PGY1 2. Diabetes have an increased CV risk, an LDL-C reduction of at least 40 minutes through childhood 3 to times! 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